| 引用本文: | 马臻1,2;王尊元2;郑晓亮2;沈正荣2;胡永洲1.白藜芦醇类似物的合成及雌激素样活性研究[J].中国现代应用药学,2007,(5):362-365. |
| MA Zhen1,2,WANG Zun-yuan2,ZHENG Xiao-liang2,SHEN Zheng-rong2,HU Yong-zhou1.Synthesis and estrogen-like activity of resveratrol analogues[J].Chin J Mod Appl Pharm(中国现代应用药学),2007,(5):362-365. |
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| 摘要: |
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| 关键词: 白藜芦醇 类似物 合成 雌激素样活性 |
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| 基金项目:浙江省卫生厅重点项目(2002ZD001);;浙江省科技厅项目(2003F12020) |
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| Synthesis and estrogen-like activity of resveratrol analogues |
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MA Zhen1,2,WANG Zun-yuan2,ZHENG Xiao-liang2,SHEN Zheng-rong2,HU Yong-zhou1
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| Abstract: |
| OBJECTIVE To synthesize resveratrol analogues,and evaluate their estrogen-like activity in vitro.METHODS The target compounds(1-9) were prepared from substituted benzyl bromide via phosphorylation,condensatiom and demethylation,then their estrogen-like ac |
| Key words: resveratrol analogues synthesis estrogen-like activity |
