| 引用本文: | 陈公英1;包小洁1;黄劲松1;余吉仙1;陈智2.低分子量肝素下调转化生长因子转录表达及抗肝纤维化作用[J].中国现代应用药学,2007,(6):445-448. |
| CHEN Gong-ying1,BAO Xiao-jie1,HUANG Jin-song1,YU Ji-xian1,CHEN Zhi2.Down-regulating the Production of TGF-β1 and Anti-Hepatic Fibrosis by Low Molecular Heparin in Rat[J].Chin J Mod Appl Pharm(中国现代应用药学),2007,(6):445-448. |
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| 摘要: |
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| 关键词: 肝素 低分子量 肝纤维化 转化生长因子β1 |
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| 基金项目:浙江省医药卫生科技项目(2002B047);;杭州市医药卫生重点科技项目(2002A004) |
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| Down-regulating the Production of TGF-β1 and Anti-Hepatic Fibrosis by Low Molecular Heparin in Rat |
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CHEN Gong-ying1,BAO Xiao-jie1,HUANG Jin-song1,YU Ji-xian1,CHEN Zhi2
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| Abstract: |
| OBJECTIVE In this study,we investigated the effect of bopuqing calcuim,a low molecular weight(LMW)-heparin,on hepatic fibrogenesis caused by chronic carbon tetrachloride CCl4 administration in the rats.We also investigate molecular events involved in the |
| Key words: heparin low molecular weight hepatic fibrosis TGF-β1 |
