抗衰老胶囊的动物实验研究

Experimental Study of Anti-aging Capsule on Mice

关键词:  抗衰老胶囊  学习记忆  血管扩张  抗衰老

Key words:  anti-aging capsule  learning and memory  blood vessel expansion  anti-aging

摘要:

目的 研究抗衰老胶囊的药理作用。方法 用复杂水迷路法测试小鼠的学习记忆状况。分别建立记忆获得障碍病理模型、记忆巩固障碍病理模型和记忆再现缺失病理模型。将抗衰老胶囊分散于鼠饲料中制成颗粒型，定量喂食，作为治疗模型。分别测定小鼠的用药后药物对外周血管与脑血管的扩张作用；和药物的抗衰老状况。结果 抗衰老胶囊对记忆获得障碍有非常显著的治疗意义，治疗组与病理组(P＜0.01)，病理组与空白组(P＜0.01)的差异有非常显著意义。对记忆再现缺失有非常显著意义，治疗组与病理组(P＜0.01)，病理组与空白组(P＜0.01)，治疗组与空白组(P＜0.01)的差异有显著意义。结果表明抗衰老胶囊能扩张外周循环，脑内微循环，能减少小鼠脑部的脂褐质量。结论 抗衰老胶囊能使小鼠提高学习记忆的能力，能扩张外周循环，能增加对脑部的供血量，减缓衰老程度。

Abstract:

OBJECTIVE To study the pharmacological effects of the anti-aging capsule. METHODS Using complex labyrinth of water to test the situation of mice’s learning and memory. To establish the models of memory access barriers of pathological model, memory consolidation of obstacles pathological model and memory loss of the pathological model of reproduction. The anti-aging capsules were scattered around the mouse’s feed which is articles, quantitative feeding, the establishment of therapeutic models; using in vivo experimental observation microcirculation peripheral vascular drugs and the expansion of the role of cerebrovascular, analysis of blood vessel expansion; to observe the situation of slow down the aging degree. RESULTS It has a significant meaning of the treatment of anti-memory access obstacle, the treatment group and pathological group (P<0.01), pathological group and the blank group (P<0.01). The difference was significant. It also has a significant meaning of the memory again missing, the treatment group and pathological group (P<0.01), pathological group and the blank group (P<0.01). The difference was significant. To the expansion of peripheral circulation, it also has a significant meaning. Can improve the brain microcirculation, can improve the mice anti-fatigue ability. CONCLUSION Mouse anti-aging capsule can improve learning and memory abilities, the anti-fatigue ability of mice to the expansion of peripheral circulation, can increase brain blood flow, the extent of links aging.