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引用本文:刘爽,毛佳乐,邱伟文,张晓芹*.畲药地稔化学成分和药理作用研究进展[J].中国现代应用药学,2024,41(7):996-1005.
LIU Shuang,MAO Jiale,QIU Weiwen,ZHANG Xiaoqin*.Research Progress on the Chemical Constituents and Pharmacological Effect of She Medicine Melastoma Dodecandrum Lour.[J].Chin J Mod Appl Pharm(中国现代应用药学),2024,41(7):996-1005.
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畲药地稔化学成分和药理作用研究进展
刘爽, 毛佳乐, 邱伟文, 张晓芹*
丽水市中医院,浙江 丽水 323000
摘要:
地稔是畲族习用药材,是野牡丹科植物地稔Melastoma dodecandrum Lour.的地上部分,含有脂肪酸、有机酸、多糖、挥发油、黄酮、鞣质、三萜、甾体等化学成分,具有抗氧化、降血糖、血脂、抗炎镇痛、止血凝血、抑菌等多种药理作用,可用于消化道出血、崩漏及糖尿病等疾病。本文主要对地稔的化学成分和药理作用研究进展进行了系统综述,为地稔的质量评价研究和产品开发提供科学依据。
关键词:  地稔  活性成分  药理作用  畲药
DOI:10.13748/j.cnki.issn1007-7693.20223893
分类号:R285.1
基金项目:浙江省自然科学基金项目(LBY22H280001);丽水市公益性项目(2021GYX18);丽水市重点研发项目(2021ZDYF16)
Research Progress on the Chemical Constituents and Pharmacological Effect of She Medicine Melastoma Dodecandrum Lour.
LIU Shuang, MAO Jiale, QIU Weiwen, ZHANG Xiaoqin*
Lishui Hospital of Traditional Chinese Medicine, Lishui 323000, China
Abstract:
The plant Melastoma dodecandrum Lour. is an ingredient used in She medicine that belongs to the Melastomacea family. Its main chemical components include fatty acids, organic acids, polysaccharides, volatile oils, flavonoids, tannins, triterpenes, steroids and other chemical components. Various pharmacological properties of this herbal medicine have been proved, such as anti-oxidation, hypoglycemic, blood lipid, anti-inflammatory and analgesic, hemostasis and coagulation, and antibacterial effects. Clinical studies have shown that it can be used for diseases such as gastrointestinal bleeding, metrorrhagia and diabetes. This article mainly reviews the research progress of the chemical components, pharmacological effects and clinical application of Melastoma dodecandrum, and provides theoretical guidance and practical value for the development, application and clinical research of Melastoma dodecandrum.
Key words:  Melastoma dodecandrum Lour.  active ingredient  pharmacological effects  SHE medicine
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