引用本文: | 许丹倩;徐振元;李淑玲1.间三氟甲基苯胺的合成[J].中国现代应用药学,1998,(2):33-35. |
| Xu Danqan(Cu DQ),Xu Zhenyuan(Xu ZY),Li Shuling (Li SL).Preparation of m-(trifluoromethyl) aniline[J].Chin J Mod Appl Pharm(中国现代应用药学),1998,(2):33-35. |
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摘要: |
以三氟甲苯为起始原料,经混酸硝化和加氢还原反应合成间三氟甲基苯胺,总收率达83%,产品纯度98%以上。 |
关键词: 间三氟甲基苯胺 医药中间体 合成 |
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Preparation of m-(trifluoromethyl) aniline |
Xu Danqan(Cu DQ),Xu Zhenyuan(Xu ZY),Li Shuling (Li SL)
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Abstract: |
m-(trifluoromethyl) aniline was prepared, starting from trifuoromethylbenzene, through nitration with mixed acid and raney ni-catahyzed hydrogenation. The total yield achived 83%, and the purity is over 98% . |
Key words: m-(trifluoromethyl) aniline,intennediate for phannaceuticals,synthesis |