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| 摘要: |
| 目的:合成塞曲司特并对其合成工艺进行改进。方法:以庚二酸单乙酯为起始原料,经氯化、付-克反应、还原、水解、缩合等步骤合成了塞曲司特。结果:五步反应的总收率为6 4% ,所得产物经熔点、红外光谱和核磁共振确证。结论:此合成工艺可行,具有工业化生产价值 |
| 关键词: 塞曲司特 合成 |
| DOI： |
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| Synthesis of seratrodast |
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Huang Jiawei
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| Abstract: |
| OBJECTIVE: To Synthesize seratrodast and improve the synthetic process. METHODS: Seradtrodast was synthesized by steps of Chlorization Friedel Crafts reaction, reduction, hydrolysis and condensation from monoethyl pimelate. RESULTS: The total yield was 6 |
| Key words: Seratrodast, synthesis |
