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摘要: |
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关键词: N+-葡萄糖醛酸缀合 物种差异 尿苷-5’-二磷酸葡萄糖醛酸缀合转移酶 II相代谢 叔胺 |
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基金项目:国家自然科学基金 (C30100232);;浙江省自然科学基金 (C300487);;浙江省卫生厅优秀青年科技人才专项基金(420001-W10114) |
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Species differences in N+-glucuronidation |
CHEN Ya-kun, LI Xin, ZENG Su
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Abstract: |
OBJECTIVE To summarize species differences in N+-glucuronidation. METHOD Compare N+-glucuronidations of aliphatic tertiary amines, piperidines, piperazines, pyridines, imidazoles and triazines in different species, with substrates classified according t |
Key words: N+-glucuronidation species differences UDP-glucuronosyltransferase phase II metabolism tertiary amines |