| 引用本文: | 崔宏杰1,2;吉爱国2;李从发3.以磺酰化β-环糊精为手性选择剂高效毛细管电泳拆分手性药物中间体[J].中国现代应用药学,2004,(3):188-190. |
| CUI Hong-jie, JI Ai-guo, LI Cong-fa.High performance capillary electrophoresis separation of chiral drug intermediates with sulfated-β-cyclodextrin as chiral selector[J].Chin J Mod Appl Pharm(中国现代应用药学),2004,(3):188-190. |
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| 摘要: |
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| 关键词: 高效毛细管电泳 磺酰化β-环糊精 手性拆分 |
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| 基金项目:山东省自然科学基金(No:Y2000C21);;教育部留学人员科研启动基金 (No:05200105)资助 |
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| High performance capillary electrophoresis separation of chiral drug intermediates with sulfated-β-cyclodextrin as chiral selector |
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CUI Hong-jie, JI Ai-guo, LI Cong-fa
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| Abstract: |
| OBJECTIVE To develop a method for the separation of the enantiomers of two chiral drug intermediates-phenylethanediol, styrene oxide by capillary electrophoresis. METHOD Phosphate-triethylamine buffer (pH 2.5) was used as the electrophoresis solution. |
| Key words: high performance capillary electrophoresis, sulfated-β-cyclodextrin, chiral separation |
