引用本文: | 赵妍1;邓意辉2;孟胜男1;王欣1.硫酸长春新碱空白脂质体的稳定性研究[J].中国现代应用药学,2007,(6):477-479. |
| ZHAO Yan1,DENG Yi-hui2,MENG Sheng-nan1,WANG Xin1.Stability Study on Vincristine Sulfate-Blank Liposomes[J].Chin J Mod Appl Pharm(中国现代应用药学),2007,(6):477-479. |
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关键词: 硫酸长春新碱 脂质体 高效液相色谱-蒸发光散射检测器 氢化大豆磷脂 pH梯度法 |
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Stability Study on Vincristine Sulfate-Blank Liposomes |
ZHAO Yan1,DENG Yi-hui2,MENG Sheng-nan1,WANG Xin1
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Abstract: |
OBJECTIVE To study the physical and chemical stability of vincristine sulfate-blank liposomes.METHODS HPLC-ELSD was applied to determine the content of HSPC,and particle size equipment was applied to determine the particle diameter.We used cation exchange |
Key words: vincristine liposome HPLC-ELSD hydrogenated soya phosphatidylcholine pH gradients method |