引用本文: | 高志刚1;邹全明2;刘凤英3;曹向光1.重组幽门螺杆菌尿素酶B亚单位鼻腔免疫凝胶剂的研制[J].中国现代应用药学,2007,(6):479-482. |
| GAO Zhi-gang1,ZOU Quan-ming2,LIU Feng-ying3,CAO Xiang-guang1.Preparation of Intranasal Immunization Gel Containing Recombinant Helicobacter Pylori Urease B[J].Chin J Mod Appl Pharm(中国现代应用药学),2007,(6):479-482. |
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关键词: 重组幽门螺杆菌尿素酶B亚单位 卡泊波凝胶剂 鼻腔免疫 |
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基金项目:国家“863”计划资助项目(2001AA215161) |
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Preparation of Intranasal Immunization Gel Containing Recombinant Helicobacter Pylori Urease B |
GAO Zhi-gang1,ZOU Quan-ming2,LIU Feng-ying3,CAO Xiang-guang1
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Abstract: |
OBJECTIVE To prepare Gel vaecine Containing recombine Helicobacter pylori UreB(rUreB)and study it's physical properties and immune efficiency by nasal route.METHODS The gel was prepared by carbopol.Sodium deoxycholate was applied to help the absorption of |
Key words: Helicobacter pylori Urease B carbopol gel intranasal immunization |