嵊州刺果毛茛的化学成分研究

Studies on the Chemical Constituents in Ranunculus muricatus L.

关键词:  刺果毛茛  豆甾-4-烯-3，6-二酮  豆甾醇  白头翁素  七叶内酯二甲醚  β-谷甾醇  原儿茶醛  原儿茶酸  木犀草素

Key words:  Ranunculus muricatus L.  stigmasta-4-ene-3,6-dione  stigmasterol  anemonin  scoparone  β-sitostero1  protocatechuic aldehyde  protocatechuic acid  luteolin

摘要:

目的对嵊州刺果毛茛的化学成分进行分离和结构鉴定。方法采用溶剂提取和各种色谱法分离得到8个化合物，运用多种波谱技术鉴定其化学结构。结果8个化合物分别鉴定为豆甾-4-烯-3，6-二酮(I)、豆甾醇(II)、白头翁素(Ⅲ)、七叶内酯二甲醚(IV)、β-谷甾醇(V)、原儿茶醛(VI)、原儿茶酸(Ⅶ)和木犀草素(Ⅷ)。结论化合物 I，Ⅳ，V，Ⅵ为首次从刺果毛茛中分离得到。

Abstract:

OBJECTIVE To isolate and determine the chemical constituents from Shengzhou Ranunculus muricatu L. . METHODS Eight compounds were isolated and purified by extraction and different kinds of column chromatography. The structures were determined on the basis of extensive spectral analysis such as EI-MS， 1H-NMR，13C-NMR and DEPT. RESULTS The structures were elucidated as stigmasta-4-ene-3，6-dione(I)，stigmasterol(Ⅱ)，anemonin (Ⅲ)，scoparone (IV)，β-sitostero1(V), protocatechuic aldehyde (Ⅵ)，protocatechuic acid(Ⅶ) and 1uteolin (Ⅷ), respectively. CONCLUSION Compounds( I，Ⅳ，V，Ⅵ) were isolated from Ranunculus muricatus for the first time.