天然高分子聚合物胶束的研究进展

Progress in the Research of Natural Polymer Micelle

关键词:  聚合物胶束  天然高分子材料  药用载体

Key words:  polymer micelle  natural polymer materials  drug carrier

摘要:

聚合物胶束作为药物载体，具有稳定性好，增加难溶性药物溶解度，使药物靶向肿瘤部位并缓慢释放，降低不良反应，提高药物生物利用度等优点，是一种优良的载药系统。天然高分子材料由于来源丰富，生物相容性好，降解产物对人体无毒而备受重视。通过查阅文献，笔者综述了天然高分子材料聚合物胶束的研究进展。

Abstract:

As an excellent drug carrier, polymer micelle possesses the following advantages: good stability, increasing solubility of insoluble drugs, making drugs target tumor site and release slowly, reducing drug toxicity, improving drug bioavailability and so on. Natural materials attract much attention for their abundant resource, good biocompatibility, innocuity to human bodies of their degradation products. Depending on the literature, this paper summarizes the progress in research of natural polymer micelle.