引用本文: | 王小娟,留良吾,徐小岗,郑志宏.HPLC-ELSD测定爱可福颗粒中的黄芪甲苷[J].中国现代应用药学,2010,27(9):842-844. |
| .Determination of Astragaloside Ⅳ in Aikefu Granules by HPLC-ELSD[J].Chin J Mod Appl Pharm(中国现代应用药学),2010,27(9):842-844. |
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摘要: |
目的 建立爱可福颗粒的定量质控方法。方法 采用HPLC-ELSD测定爱可福颗粒中黄芪甲苷的含量。结果 黄芪甲苷进样量在0.64~20.48 μg内呈良好的线性关系,平均回收率为97.78%,RSD=1.12%(n=6)。结论 该方法简便,重复性好,可用于控制爱可福颗粒的质量。 |
关键词: HPLC-ELSD 爱可福颗粒 黄芪甲苷 含量测定 |
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Determination of Astragaloside Ⅳ in Aikefu Granules by HPLC-ELSD |
WANG Xiaojuan1 LIU Liangwu2 XU Xiaogang3 ZHENG Zhihong3
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Abstract: |
OBJECTIVE To establish a method for the determination of astragaloside Ⅳ in Aikefu granules by HPLC-ELSD. METHODS The content of astragaloside Ⅳ was determined by HPLC-ELSD. RESULTS A good linearity was observed for astragaloside Ⅳ in the range of 0.64-20.48 μg. The average recovery of astragaloside Ⅳ was 97.78% with RSD=1.12%(n=6). CONCLUSION The method is simple, accurate and reiable. It can be used for the quality control of granules. |
Key words: HPLC-ELSD Aikefu granules astragaloside Ⅳ content determination |