| 引用本文: | 朱斌,刘涛,蒋受军,韦涛.Mg2+在药物无菌检查中的应用[J].中国现代应用药学,2010,27(11):1031-1033. |
| .The Study on the Application of Mg2+ in the Sterility Test[J].Chin J Mod Appl Pharm(中国现代应用药学),2010,27(11):1031-1033. |
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| 摘要: |
| 目的 探讨Mg2+作为中和剂在无菌检查中的合理应用。方法 添加不同浓度Mg2+，观察对培养基、稀释剂和冲洗液性状、以及对微生物生长的影响。结果 以规定验证菌试验，对Mg2+最敏感验证菌为铜绿假单孢菌。结论 Mg2+作为中和剂应用于无菌检查，其使用方式、使用量(浓度)应进行考察，选择合理的应用方式。 |
| 关键词: Mg2+ 喹诺酮 中和剂 无菌检查 |
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| The Study on the Application of Mg2+ in the Sterility Test |
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ZHU Bin LIU Tao JIANG Shoujun WEI Tao
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| Abstract: |
OBJECTIVE To find the equitable way of Mg2+ using in sterility test.
METHODS Experiments were conducted with culture medium, diluting agent, washing fluid compounded with different concentration of Mg2+. RESULTS The most susceptible bacterium to Mg2+ was Pseudomonas aeruginosa.
CONCLUSION Mg2+ as a diluent in sterility test should be used in a reasonable way. |
| Key words: Mg2+ quinolones diluent sterility test |
