当归不同炮制饮片“性-效-物”差异性分析

Analysis on the differences of medicinal properties-efficacy-quality markers of different decoction pieces of Angelica sinensis

关键词:  当归饮片  药性  药效  质量标志物#$TAB

Key words:  angelica sinensis decoction pieces  medicinal properties  efficacy  quality markers

摘要:

当归临床常用的炮制饮片有4种，即生当归、酒当归、土炒当归和当归炭，不同当归炮制饮片的药性、药效和主要药效成分存在一定的差异，现代研究多基于“成分-药效”的二元变化模式，揭示了当归不同炮制饮片主要药效的差异和药效物质基础的变化特点，但对炮制存性或炮制改性的研究较少，本文结合现有的研究结果，从药性、药效、物质基础三方面分析了当归不同炮制饮片的质量属性，探讨“性-效-物”的变化规律，为当归的炮制理论提供证据支持。

Abstract:

The 4 kinds of processed decoction pieces commonly used in the clinical practice of Angelica sinensis, raw A. Sinensis, wine-processed A. Sinensis, soil-stir-baked A. sinensis and A. Sinensis Carbonisata, there are certain differences in the medicinal properties, efficacy and main pharmacodynamic components of different decoction pieces of A. sinensis, new research is mostly based on the binary change mode of "ingredient - efficacy", revealing the differences in the main pharmacodynamics of different processed decoction pieces of A. sinensis and the change rule of the material basis of pharmacodynamics, but there are few explorations of processing properties or processing modifications. This paper analyzes the quality attributes of different decoction pieces of A. sinensis from drug properties, efficacy, and material basis of curative effect, and the depth discussion of transmission change rule "nature-effect-matter" was completed, so as to provide evidence support for the processing theory of A. sinensis.