| 引用本文: | 芦小燕,戴幼琴,陈维,龚燕波,任燕萍.基于循证的静脉用质子泵抑制剂预防应激性溃疡的合理性评价标准的建立[J].中国现代应用药学,2015,32(12):1481-1484. |
| LU Xiaoyan,DAI Youqin,CHEN Wei,GONG Yanbo,REN Yanping.Setting of the Evidence-based Criteria to Evaluate the Use of Intravenous Proton Pump Inhibitors in Stress Ulcer Prophylaxis[J].Chin J Mod Appl Pharm(中国现代应用药学),2015,32(12):1481-1484. |
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| 摘要: |
| 目的 通过循证医学方法制订静脉用质子泵抑制剂(intravenous proton pump inhibitors，IV PPIs)预防应激性溃疡(stress ulcer prophylaxis，SUP)的合理性评价的标准。方法 将临床问题进行转化，制定检索策略，以检索词“注射用质子泵抑制剂”、“预防应激性溃疡”、“intravenous proton pump inhibitors”、“stress ulcer prophylaxis”计算机检索数据库 The Cochrane Library、PubMed、CNKI、VIP、WanFang Data，检索时限均为1989—2014年。筛选文献，选择最佳的临床证据进行精读。结果 制订IV PPIs用于SUP的合理性评价的标准和医嘱点评表。结论 利用循证医学方法结合医院实际制订医院IV PPIs预防用合理性评价标准是可行的。 |
| 关键词: 循证 标准 静脉用质子泵抑制剂 预防应激性溃疡 合理性 |
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| 基金项目:浙江省自然科学基金青年基金项目(LQ13B020005)；宁波市自然基金项目(2015A610284)；浙江省药学会医院药学专项科研基金项目(2014ZYY34) |
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| Setting of the Evidence-based Criteria to Evaluate the Use of Intravenous Proton Pump Inhibitors in Stress Ulcer Prophylaxis |
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LU Xiaoyan1, DAI Youqin1, CHEN Wei2, GONG Yanbo1, REN Yanping1
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1.Ningbo No.2 Hospital, Ningbo 315010, China;2.Zhejiang Pharmaceutical College, Ningbo 315100, China
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| Abstract: |
| OBJECTIVE To set up the criteria in our hospital to evaluate the rationality of using intravenous proton pump inhibitors in stress ulcer prophylaxis. METHODS To turn clinical problems, retrieval strategy. Search terms “intravenous proton pump inhibitors”, “stress ulcer prophylaxis”(in English and in Chinese) were used to search The Cochrane Library, PubMed, CNKI, VIP, WanFang Data(1989-2014). Literatures were screened to choose the best clinical evidence to intensive read. RESULTS The criteria and the doctor’s advice comments table in our hospital were established. CONCLUSION Using evidence-based medicine method and combining with our actual hospital to set the standards of IV PPIs prevention with rationality evaluation are feasible. |
| Key words: evidence-based criteria intravenous proton pump inhibitors stress ulcer prophylaxis rationality |
