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引用本文:王慧丽,李燕,郑丽娜,王春艳,姜海英,杨丽君.蒲药灌肠液辅助血府逐瘀胶囊综合治疗气滞血瘀型慢性盆腔炎的临床试验[J].中国现代应用药学,2017,34(9):1322-1325.
WANG Huili,LI Yan,ZHENG Lina,WANG Chunyan,JIANG Haiying,YANG Lijun.Clinical Study on the Qi Stagnation and Blood Stasis Type of Chronic Pelvic Inflammation Treat by Xuefuzhuyu Capsules Plus Puyao Rectal Solution[J].Chin J Mod Appl Pharm(中国现代应用药学),2017,34(9):1322-1325.
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蒲药灌肠液辅助血府逐瘀胶囊综合治疗气滞血瘀型慢性盆腔炎的临床试验
王慧丽1, 李燕1, 郑丽娜1, 王春艳1, 姜海英2, 杨丽君3
1.唐山市妇幼保健院, 药剂科, 河北 唐山 063000;2.唐山市妇幼保健院, 妇科, 河北 唐山 063000;3.唐山市妇幼保健院, 中医科, 河北 唐山 063000
摘要:
目的 研究蒲药灌肠液辅助血府逐瘀胶囊综合治疗气滞血瘀型慢性盆腔炎的临床疗效,为其临床应用提供科学依据。方法 气滞血瘀型慢性盆腔炎患者122例,随机分为对照组和试验组。对照组口服血府逐瘀胶囊,试验组口服血府逐瘀胶囊同时辅助蒲药灌肠液治疗,2个疗程后比较2组治疗效果。结果 试验组愈显率为69.4%,总有效率为93.6%;对照组愈显率为43.3%,总有效率为81.6%;两组比较差异有统计学意义(P<0.05)。试验组在改善中医证候和局部体征方面,降低高切全血黏度、血浆黏度和红细胞积压方面优于对照组,差异有统计学意义(P<0.05)。结论 蒲药灌肠液辅助血府逐瘀胶囊综合治疗气滞血瘀型慢性盆腔炎,可以明显提高治疗效果,且能改善患者血液流变性,值得临床推广。
关键词:  慢性盆腔炎  气滞血瘀  血府逐瘀胶囊  蒲药灌肠液
DOI:10.13748/j.cnki.issn1007-7693.2017.09.023
分类号:R969.4
基金项目:
Clinical Study on the Qi Stagnation and Blood Stasis Type of Chronic Pelvic Inflammation Treat by Xuefuzhuyu Capsules Plus Puyao Rectal Solution
WANG Huili1, LI Yan1, ZHENG Lina1, WANG Chunyan1, JIANG Haiying2, YANG Lijun3
1.Tangshan Maternal and Child Health Hospital, Department of Pharmacy, Tangshan 063000, China;2.Tangshan Maternal and Child Health Hospital, Department of Gynaecology, Tangshan 063000, China;3.Tangshan Maternal and Child Health Hospital, Department of Traditional Chinese Medicine, Tangshan 063000, China
Abstract:
OBJECTIVE To corroborate the therapeutic effects for Qi stagnation and blood stasis type of chronic pelvic inflammation under the treatment of Xuefuzhuyu capsules plus Puyao rectal solution, and provide scientific basis for its clinical application. METHODS The 122 patients of Qi stagnation and blood stasis type of chronic pelvic inflammation were randomly assigned into two groups named control and experimental group, respectively. The control group were orally administrated with Xuefuzhuyu capsules only. The experimental group were treated with Xuefuzhuyu capsules together with Puyao rectal solution. The therapeutic effects between groups were compared at the end of two courses of treatment. RESULTS In the experimental group, the remarkably effective rate was 69.4% and the total efficiency was 93.6%; in the control group, the remarkably effective rate was 43.3% and the total efficiency was 81.6%, the differences were statistically significant with P<0.05. The experimental group were better than the control group in the improvement of TCM syndromes and the local signs, in reducing the high shear whole blood viscosity, plasma viscosity and hematocrit, the differences were statistically significant with P<0.05. CONCLUSION The therapeutic effect for Qi stagnation and blood stasis type of chronic pelvic inflammation under the treatment of Xuefuzhuyu capsules can be significantly enhanced with Puyao rectal solution. The drug combination can strengthen the effect, improve the blood rheology, is worth further promotion.
Key words:  chronic pelvic inflammation  Qi stagnation and blood stasis  Xuefuzhuyu capsules  Puyao rectal solution
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